Peer-Reviewed Publications

*denotes student/trainee authors

Eating a high fat/high carbohydrate diet enhances morphine tolerance, while eating a ketogenic diet mitigates morphine withdrawal in male rats

*Beltran NM, *Sullivan LL, , *Naime GM, Minervini V, Serafine KM. (2025) European Journal of Pharmacology. doi: 10.1016/j.ejphar.2025.177709.

The effects of high fat diet consumption on morphine-induced constipation.

*Beltran NM, *Garcia TI, *Naime GM, Minervini V, Serafine KM. (2025) Behavioural Pharmacology. doi: 10.1097/FBP.0000000000000831

The effects of eating a traditional high fat/high carbohydrate or a ketogenic diet on sensitivity of female rats to morphine.

*Beltran NM, *Parra AN, *Serrano AP, *Castillo J, *Castro IM, *Elsey MK, Minervini V, Serafine KM. (2024) Journal of Pharmacology and Experimental Therapeutics. Sep 18;391(1):30-38

Effects of access condition on substance use disorder-like phenotypes in male and female rats self-administering MDPV or cocaine

Doyle MR, *Beltran NM, Bushnell MSA, Syed M, Acosta V, Desai M, Rice KC, Serafine KM, Gould GG, Daws LC, Collins GT. (2024) Drug and Alcohol Dependence, Manuscript accepted 2024, Aug 6

Insulin resistance produced by a high fat diet regimen enhances the reinforcing effects of nicotine to a greater extent in female versus male rats. 

Cruz B, Ortegon O, Matos F, Rodriguez-Crespo A, *Galindo KI, Serafine KM, Nazarian A, O’Dell LE. (2021)  Neuropharmacology, Special Issue: Vulnerabilities in Substance Abuse, 1;200:108787.doi: 10.1016/j.neuropharm.2021.108787. Epub 2021 Sept 24

Converging vulnerability factors for compulsive food and drug use. 

Serafine KM, O'Dell LE, Zorrilla EP. (2021) Neuropharmacology: 20;196:108556. doi: 10.1016/j.neuropharm.2021.108556.

Increased mood disorder symptoms, perceived stress, and alcohol use among college students during the COVID-19 pandemic.

Charles NE, Strong SJ, Burns LC, Bullerjahn MR, Serafine KM. (2021) Psychiatry Res. 296:113706.
​doi: 10.1016/j.psychres.2021.113706. 

Intermittent dietary supplementation with fish oil prevents high fat diet-induced enhanced sensitivity to dopaminergic drugs.

*Beltran NM, *Ramos J, *Galindo KI, *Echeverri JI, *Cruz B, *Hernandez-Casner C, Serafine KM​. (2021) ​Behav Pharmacol. 32(1):9-20. doi: 10.1097/FBP.0000000000000597​.

Omega-3 fatty acids and vulnerability to addiction: Reviewing preclinical and clinical evidence. 

Darcey VL, Serafine KM.  (2020) Curr Pharm Des. 26(20):2385-2401​. 

The effects of eating a high fat diet on sensitivity of male and female rats to methamphetamine and dopamine D1 receptor agonist SKF 82958.

*Ramos J, *Hardin EJ, *Grant AH, *Flores-Robles G, *Gonzalez AT, *Cruz B, *Martinez AK, *Beltran KM, Serafine KM. (2020) J Pharmacol Exp Ther. 374(1) :6-15​.

Dietary supplementation with fish oil reverses high fat diet-induced enhanced sensitivity to the behavioral effects of quinpirole.

*Hernandez-Casener C, *Woloshchuk CJ, *Poisson C, *Hussain S, *Ramos J, Serafine KM. (2019) Behav Pharamacol. 30(4):370-375.

Insulin modulates the strong reinforcing effects of nicotine and changes in insulin biomarkers in a rodent model of diabetes. 

*Cruz B, *Flores RJ, *Uribe KP, *Espinosa EJ, Spencer CT, Serafine KM, Nazarian A, O'Dell LE. (2019) ​Int J Neuropsychopharmacol. 44(6):1141-1151. 

Sex differences in high fat diet-induced striatal Akt signaling and enhanced sensitivity to the behavioral effects of dopamine D2/D3 receptor agonist quinpirole.

*Ramos J, *Hernandez-Casner C, Serafine KM. (2019) Physiology & Behavior: Special issue on Sex Differences. 203:25-32. 

Dietary supplementation with fish oil prevents high fat diet-induced enhancement of sensitivity to the behavioral effects of quinpirole. ​
*Hernandez-Casner C, *Ramos J, Serafine KM. (2017) Behav Pharmacol. 28(6): 477-484.

Characterization of the discriminative stimulus effects of lorcaserin in rats.

Serafine KM, Rice KC, France CP. (2016) ​J Exp Anal Behav. 106: 107-116. 

Dietary supplementation with fish oil prevents high fat diet-induced enhancement of sensitivity to the locomotor stimulating effects of cocaine in adolescent female rats.
Serafine KM, *Labay C, France CP. (2016) Drug Alcohol Depen. 165: 45-52.

Directly observable behavioral effects of lorcaserin in rats.

Serafine KM, Rice KC, France CP. (2015) J Pharmacol Exp Ther. ​355: 381-385.

Drinking sucrose or saccharin enhances sensitivity of rats to quinpirole-induced yawning.
Serafine KM​, *Bentley TA, *Kilborn DJ, Koek W, France CP. (2015) Eur J Pharmacol, 764: 529-536. 

Eating high fat chow, but not drinking sucrose or saccharin, enhances the development of sensitization to the locomotor effects of cocaine in adolescent female rats. 
Serafine KM, *Bentley TA, Koek W, France CP. (2014) Behav Pharmacol, 26: 321-325. 

Eating high fat chow and the behavioral effects of direct- and indirect-acting dopamine receptor agonists in female rats.
Serafine KM, *Bentley TA, *Grenier AE, France CP. (2014) Behav Pharmacol, 25:287-295. 

Restricted access to standard or high fat chow alters sensitivity of rats to the 5-HT2A/2C receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM).
Serafine KM, France CP. (2014) Behav Pharmacol, 25:44-52. 

The effects of 5-HT3 antagonism on cocaine-induced conditioned taste aversions. 

*Briscione MA, Serafine KM, *Merluzzi AM, Rice KC, Riley AL. (2013) Pharmacol Biochem Behav, 105: 112–117. 

Dopamine mediates cocaine-induced conditioned taste aversions as demonstrated with cross-drug preexposure to GBR 12909. 
Serafine KM, *Briscione MA, Rice KC, Riley AL. (2012) Pharmacol Biochem Behav, 102: 269-274. 

The effects of haloperidol on cocaine-induced conditioned taste aversions.

Serafine KM, *Briscione MA, Riley AL. (2012) Physiol Behav, 105: 1161-1167.  

Preexposure to cocaine attenuates aversions induced by both cocaine and fluoxetine: Implications for the basis of cocaine-induced conditioned taste aversions.
Serafine KM, Riley AL.(2010) . Pharmacol Biochem Behav, 95: 230-234. 

Possible role of norepinephrine in cocaine-induced conditioned taste aversions. 

Serafine KM, Riley AL.(2009) .Pharmacol Biochem Behav, 92: 111-116. 

Genetic and early environmental contributions to alcohol’s aversive and physiological effects.

Roma PG, Rinker JA, Serafine KM, Chen SA, Barr CS, Cheng K, Rice KC, Riley AL. (2008) Pharmacol Biochem Behav, 91: 134-139. 

Edited Book Chapters

Cocaine-induced conditioned taste aversions: Role of monoamine reuptake inhibition.

In Hall, FS. ed. 2013 Serotonin: Biosynthesis, Regulation and Health Implications, Hauppauge, NY: NOVA Science Publishers, Inc. ISBN: 978-1-62417-636-4